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2011

Architecture and assembly of a divergent member of the ParM family of bacterial actin like proteins. Rivera CR, Kollman JM, Polka JK, Agard DA, Mullins RD. J Biol Chem. 2011 Feb 21.
Abstract | Full Text

2010

VASP is a processive actin polymerase that requires monomeric actin for barbed end association. Hansen SD, Mullins RD. J Cell Biol. 2010 Nov 1;191(3):571-84.
Abstract | Full Text

2009

In silico reconstitution of actin-based symmetry breaking and motility. Dayel MJ, Akin O, Landeryou M, Risca V, Mogilner A, Mullins RD. PLoS Biol. 2009 Sep;7(9).
Abstract | Full Text

Structural polymorphism of the ParM filament and dynamic instability. Galkin VE, Orlova A, Rivera C, Mullins RD, Egelman EH. Structure. 2009 Sep 9. 17(9) pp. 1253 - 1264.
Abstract

The structure and assembly dynamics of plasmid actin AlfA imply a novel mechanism of DNA segregation. Polka JK, Kollman JM, Agard DA, Mullins RD. J Bacteriol. 2009 Aug 7.
Abstract | Full Text

p53-cofactor JMY is a multifunctional actin nucleation factor. Zuchero JB, Coutts AS, Quinlan ME,Thangue NB, Mullins RD. Nat Cell Biol. 2009 Apr;11(4):451-9. Epub 2009 Mar 15.
Abstract | Full Text

2008

Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments. LeClaire LL 3rd, Baumgartner M, Iwasa JH, Mullins RD, Barber DL. J Cell Biol. 2008 Aug 25;182(4):647-54.

The pathogen protein EspF(U) hijacks actin polymerization using mimicry and multivalency. Sallee NA, Rivera GM, Dueber JE, Vasilescu D, Mullins RD, Mayer BJ, Lim WA. Nature. 2008 Aug 21;454(7207):1005-8. Epub 2008 Jul 23.

Protein-nanocrystal conjugates support a single filament polymerization model in R1 plasmid segregation. Choi CL, Claridge SA, Garner EC, Alivisatos AP, Mullins RD. J Biol Chem. 2008 Oct 17;283(42):28081-6. Epub 2008 Jul 24.

Capping protein increases the rate of actin-based motility by promoting filament nucleation by the Arp2/3 complex. Akin O, Mullins RD. Cell. 2008 May 30;133(5):841-51.
Abstract | Full Text

2007

In vivo visualization of type II plasmid segregation: bacterial actin filaments pushing plasmids. Campbell CS, Mullins RD. J Cell Biol. 2007 Dec 3;179(5):1059-66. Epub 2007 Nov 26.

The structure of bacterial ParM filaments. Orlova A, Garner EC, Galkin VE, Heuser J, Mullins RD, Egelman EH. Nat Struct Mol Biol. 2007 Oct;14(10):921-6. Epub 2007 Sep 16.

Regulatory interactions between two actin nucleators, Spire and Cappuccino. Quinlan ME, Hilgert S, Bedrossian A, Mullins RD, Kerkhoff E. J Cell Biol. 2007 Oct 8;179(1):117-28.

Reconstitution of DNA segregation driven by assembly of a prokaryotic actin homolog. Garner EC, Campbell CS, Weibel DB, Mullins RD. Science. 2007 Mar 2;315(5816):1270-4.

Spatial and temporal relationships between actin-filament nucleation, capping, and disassembly. Iwasa JH, Mullins RD. Curr Biol. 2007 Mar 6;17(5):395-406.

2006

Targeted wild-type and jerker espins reveal a novel, WH2-domain-dependent way to make actin bundles in cells. Loomis PA, Kelly AE, Zheng L, Changyaleket B, Sekerková G, Mugnaini E, Ferreira A, Mullins RD, Bartles JR. J Cell Sci. 2006 Apr 15;119(Pt 8):1655-65. Epub 2006 Mar 28.

2005

Actin binding to the central domain of WASP/Scar proteins plays a critical role in the activation of the Arp2/3 complex. Kelly AE, Kranitz H, Dötsch V, Mullins RD. J Biol Chem. 2006 Apr 14;281(15):10589-97. Epub 2005 Dec 23.

Drosophila Spire is an actin nucleation factor. Quinlan ME, Heuser JE, Kerkhoff E, Mullins RD. Nature. 2005 Jan 27;433(7024):382-8.

2004

Dynamic instability in a DNA-segregating prokaryotic actin homolog. Garner EC, Campbell CS, Mullins RD. Science. 2004 Nov 5;306(5698):1021-5.

Activation of Arp2/3 complex: addition of the first subunit of the new filament by a WASP protein triggers rapid ATP hydrolysis on Arp2. Dayel MJ, Mullins RD. PLoS Biol. 2004 Apr;2(4):E91. Epub 2004 Apr 13.

2001

Arp2/3 complex requires hydrolyzable ATP for nucleation of new actin filaments. Dayel MJ, Holleran EA, Mullins RD. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14871-6.

Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities. Zalevsky J, Lempert L, Kranitz H, Mullins RD. Curr Biol. 2001 Dec 11;11(24):1903-13.

Activation of the Arp2/3 complex by the Listeria acta protein. Acta binds two actin monomers and three subunits of the Arp2/3 complex. Zalevsky J, Grigorova I, Mullins RD. J Biol Chem. 2001 Feb 2;276(5):3468-75. Epub 2000 Oct 11.

Calcium spiking activity and baseline calcium levels in ROS 17/2.8 cells exposed to extremely low frequency electromagnetic fields (ELF EMF). Shahidain R, Mullins RD, Sisken JE. Int J Radiat Biol. 2001 Feb;77(2):241-8.

2000

Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks. Blanchoin L, Pollard TD, Mullins RD. Curr Biol. 2000 Oct 19;10(20):1273-82.

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex. Prehoda KE, Scott JA, Mullins RD, Lim WA. Science. 2000 Oct 27;290(5492):801-6.

Mechanisms underlying spontaneous calcium spiking in aequorin-loaded ROS 17/2.8 cells. Mullins RD, Sisken JE. Bioelectromagnetics. 2000 Jul;21(5):329-37.

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. DeFea KA, Zalevsky J, Thoma MS, Déry O, Mullins RD, Bunnett NW. J Cell Biol. 2000 Mar 20;148(6):1267-81.

1999

Rho-family GTPases require the Arp2/3 complex to stimulate actin polymerization in Acanthamoeba extracts. Mullins RD, Pollard TD. Curr Biol. 1999 Apr 22;9(8):405-15.

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex. Machesky LM, Mullins RD, Higgs HN, Kaiser DA, Blanchoin L, May RC, Hall ME, Pollard TD. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3739-44.

1998

Arp2/3 complex from Acanthamoeba binds profilin and cross-links actin filaments. Mullins RD, Kelleher JF, Xu J, Pollard TD. Mol Biol Cell. 1998 Apr;9(4):841-52.

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Mullins RD, Heuser JA, Pollard TD. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6181-6.

Arp2/3 complex from Acanthamoeba binds profilin and cross-links actin filaments. Mullins RD, Kelleher JF, Xu J, Pollard TD. Mol Biol Cell. 1998 Apr;9(4):841-52.

1997

Structure, subunit topology, and actin-binding activity of the Arp2/3 complex from Acanthamoeba. Mullins RD, Stafford WF, Pollard TD. J Cell Biol. 1997 Jan 27;136(2):331-43.

1993

Serum- and bradykinin-induced calcium transients in familial Alzheimer's fibroblasts. McCoy KR, Mullins RD, Newcomb TG, Ng GM, Pavlínková G, Polinsky RJ, Nee LE, Sisken JE. Neurobiol Aging. 1993 Sep-Oct;14(5):447-55.

Altered calcium regulation in SV40-transformed Swiss 3T3 fibroblasts. Newcomb TG, Mullins RD, Sisken JE. Cell Calcium. 1993 Jul;14(7):539-49.

Design and characterization of a system for exposure of cultured cells to extremely low frequency electric and magnetic fields over a wide range of field strengths. Mullins RD, Sisken JE, Hejase HA, Sisken BF. Bioelectromagnetics. 1993;14(2):173-86.

insight

Cell mechanics and the cytoskeleton. Fletcher DA, Mullins RD. Nature. 2010 Jan 28.

reviews

Cytoskeletal mechanisms for breaking cellular symmetry. Mullins RD. Cold Spring Harb Perspect Biol. 2010 Jan;2(1).

Bacterial chromosome segregation. Mullins RD. Annu Rev Cell Dev Biol. 2009 Jan 12.

Trapping fugitive filament formers. Mullins RD. Structure. 2008 May;16(5):661-3.

Cellular control of actin nucleation. Welch MD, Mullins RD. Annu Rev Cell Dev Biol. 2002;18:247-88. Epub 2002 Apr 2.

Actin dynamics. Pollard TD, Blanchoin L, Mullins RD. J Cell Sci. 2001 Jan;114(Pt 1):3-4.

Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Pollard TD, Blanchoin L, Mullins RD. Annu Rev Biophys Biomol Struct. 2000;29:545-76.

How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures. Mullins RD. Curr Opin Cell Biol. 2000 Feb;12(1):91-6.

Actin assembly mediated by Arp2/3 complex and WASP family proteins. Mullins RD, Machesky LM. Methods Enzymol. 2000;325:214-37.

Structure and function of the Arp2/3 complex. Mullins RD, Pollard TD. Curr Opin Struct Biol. 1999 Apr;9(2):244-9.

Purification and assay of the Arp2/3 complex from Acanthamoeba castellanii. Kelleher JF, Mullins RD, Pollard TD. Methods Enzymol. 1998;298:42-51.

Mullins, R.D. and Pollard, T.D. (1999) Arp2/3 complex. In: Guidebook to the cytoskeletal and motor proteins, Second Edition, (T. Kreis and R. Vale, eds) Oxford University Press, Oxford. pp. 45-48.

Actin' like actin? Mullins RD, Kelleher JF, Pollard TD. Trends Cell Biol. 1996 Jun;6(6):208-12.